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Welcome to the REGARDS Study

 Latest News

Targeting cardiovascular disease risk factors may be important across a lifetime

October 3, 2016 - New REGARDS findings suggest that all adults, including those over 65, should be mindful of risk factors for cardiovascular disease. The results were published in the Journal of the American Geriatric Society. 

"As life expecatancy continues to increase, we need to improve risk factor prevention and management for stroke and heart disease across the lifespan, including for those adults over the age of 65," said Claudia Moy, Ph.D., acting director of the Office of Clinical Research at NINDS, and on of the study authors. "The latest findings from the REGARDS study reveal that no age group is immune to risk factors related to cardiovascular disease and that prevention efforts should target all adults." Read full article

Cardiovascular risk linked to profession in older workers

PHOENIX, March 1, 2016 — Workers age 45 and older in sales, office-support or service occupations appear to have more risk factors for heart disease and stroke than workers in management or professional jobs, according to research presented at the American Heart Association’s Epidemiology/Lifestyle 2016 meeting.

Overall, although more than 88 percent of workers age 45 and older did not smoke and 78 percent had ideal glucose levels, fewer than 41 percent of the workers had “ideal cardiovascular health” in five other measures, and new research found wide variation in the cardiovascular risk profiles by profession. The study involved 5,566 employed men and women, black or white, who did not have a history of heart disease or stroke at the beginning of the study.  Read full article

Dr. George Howard wins award for REGARDS research

October 6, 2015 Congratulations to The National Institute of Neurological Disorders and Stroke (NINDS) grantee Dr. George Howard for winning the Ernest Just Prize, given for innovative research on health disparities among African Americans. The prize is jointly sponsored by the College of Charleston and the Medical University of South Carolina. Dr. Howard, a professor at the University of Alabama at Birmingham School of Public Health, received the award for his work on the REGARDS study. This study, sponsored by @National Institutes of Health, focuses on better understanding the factors that increase a person's risk of having a stroke, especially among African Americans. Read full article.

Dr. Judd and team study dietary patterns in the REGARDS population

Examining diet as a whole using dietary patterns as exposures is a complementary method to using single food or nutrients in studies of diet and disease. Since the generalizability of patterns across race, region, and gender in the United States has not been established, Suzanne E. Judd, PhD, associate professor in the Department of Biostatistics—along with department volunteer Abraham J. Letter, as well as James M. Shikany, DrPH, professor in the Division of Preventive Medicine—recently employed rigorous statistical analysis to empirically derive dietary patterns in a large bi-racial, geographically diverse population and to examine whether results are stable across population subgroups.

The analysis utilized data from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study—which investigates the factors that increase the risk for stroke—pertaining to 21,636 participants who completed the Block 98 Food Frequency Questionnaire. The researchers employed exploratory factor analysis and confirmatory factor analyses on 56 different food groups iteratively and examined differences by race, region, and sex to determine the optimal factor solution in the sample group.

Five dietary patterns emerged and showed strong congruence across race, sex and region: (1) the “Convenience” pattern was characterized by mixed dishes; (2) the “Plant-based” pattern by fruits, vegetables, and fish; (3) the “Sweets/Fats” pattern by sweet snacks, desserts, and fats and oils; (4) the “Southern” pattern by fried foods, organ meat, and sweetened beverages; and (5) the “Alcohol/Salads” pattern by beer, wine, liquor, and salads. Differences were most pronounced in the Southern pattern, with black participants, participants residing in the Southeast, and participants not completing high school having the highest scores. 

Future research will examine associations between these patterns and health outcomes to better understand racial disparities in disease and inform prevention efforts.

To read “Dietary Patterns Derived Using Exploratory and Confirmatory Factor Analysis Are Stable and Generalizable across Race, Region, and Gender Subgroups in the REGARDS Study,” published in December 2014 in the journal Frontiers in Nutrition, click here.